Dr. Buğra Buyrukçu

In which diseases is ozone therapy effective?

Circulatory disorders

Sensation of coldness in legs and sore foot after short walks are the signals of circulatory disorders and ozone treatment is very effective for these conditions with a proven success by numerous medical studies. It can be used in combination with conventional therapy.


Anti-aging and rejuvenation

Stress in work life, intense workload, mental and physical fatigue, all these respond very well to ozone therapy. Through activation of red and white blood cell metabolism, it provides a general well-being and people feel refreshed. Professional athletes and women benefit a lot from this treatment. Ozone increases physical strength as well.

Prevention and treatment in elderly persons

The elderly respond very well to ozone therapy. In addition to all clinical advantages, it provides better use of oxygen by tissues, stimulates the immune system and promotes body's own antioxidants and cells that fight against free radicals. In addition, as a complementary treatment, it is used to improve the quality of life.

Eye diseases

Age related circulatory disorders affect the eye causing atrophic and degenerative changes. In clinical studies (University of Siena), visual improvements were observed within 6-8 months following ozone autohemotransfusion.


Ozone therapy in cancer patients is quite successful as a complementary treatment, administered in low doses it induces biological reactions and activates the immune system, by this means immune cells produce precursor proteins including cytokines called interferon. In fact, ozone leads the body to produce its own interferon and interleukins in gradually increasing amounts. Increased immune reaction also contributes to an increase in the overall resistance and fitness of the body.

Skin infections

Ozone's fungicidal and bactericidal properties have been successfully used in drinking water for the last 100 years. These properties make medical ozone a very efficient treatment agent in combating persistent fungal and bacterial skin and mucosa lesions.

Infected wounds

Infected wounds, such as decubitus ulcers (bed sores), lower leg ulcers (ulcus cruris), stubborn diabetic wounds and gangrene, are the typical lesions where medical ozone is locally used. Here, we benefit from the disinfectant property of ozone, in other words, bactericidal and fungicidal action to obtain germ-free and clean wounds. After the cleansing of the wound, the healing process is accelerated by applying a low dose of ozone.

Intestinal Diseases

Local application of rectal ozone gas in the early period of inflammation, especially in intestinal diseases, has been proved to be very useful. In most cases 10 sessions of ozone is found to be sufficient by clinical studies.

Herpetic diseases

Herpes simplex (facial herpes) and herpes zoster (shingles) are both caused by viruses. Herpes labialis is a recurrent and unpleasant disease that is very successfully treated with combination of ozone with other medical methods. For herpes zoster, ozone is used as a complementary therapy in the form of ozonated water compresses or ozonated blood transfusion.

Liver inflammation (Hepatitis A, B, C)

Inflammation of the liver is one of the classic treatments of medical ozone. Hepatitis A can be completely cured, Hepatitis B is often chronic. In addition to conventional medical treatment methods, successful results have been obtained with ozonated blood transfusion or rectal administration of ozone/oxygen gas in a controlled manner. These methods are also performed in Hepatitis C, of which incubation period lasts for years and cannot be diagnosed until it becomes a chronic liver disease.

Inflammatory and degenerative joint diseases

Medical ozone is beneficial for inflammatory diseases stage 1 and 2 where there is no severe bone deformation. The active arthritic form of gonarthrosis (knee joint inflammation) and active arthritis of knee and shoulder joints also respond to ozone therapy. In such cases, intra-articular ozone injection is successfully performed in combination with standard medical methods. We benefit from the anti-inflammatory properties of ozone in addition to strengthening of the immune system and the activation of cartilage metabolism.

Arthritic/Rheumatic Diseases

Arthritic/rheumatic conditions include many painful and dysfunctional diseases related to the skeletal or muscular system. In general, medical ozone therapy is combined with physical therapy. In studies with rheumatoid arthritis patients, ozone major autohemotherapy is shown to be successful as a complementary therapy in non-acute conditions. The anti-inflammatory effect is of help in these cases.