First written source is the Ninova tablets written in BC3000, commenting about the products that are prepared from herbs and used for treatment. Mesopotamian Civilizations, such as Sumer, Assyria, Akkad, are known to use herbal medicine, in Chinese and Indian medicine plants have an important place. The most important person of Greek medicine Esculape and Hippocrates, the founder of modern medicine mentioned more than 400 herbal products in their books. In Islamic civilization, Ibn Sina and Al Gafini have important studies on herbal medicine. Ibn Sina's book "Canon of Medicine" gave a wide coverage to the introduction and use of therapeutic plants. Dioscorides talked about the medicinal plants of Anatolia and central Asia in his book “Knowledge of Drugs”.